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Download Poland 981 031 txt


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We merged our aDNA data with previously published datasets of 4,336 ancient individuals reported by the Reich laboratory in the Allen Ancient DNA Resource v.50.0 ( -ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data). We assembled a dataset from mostly European populations for genome-wide analyses36,45,46,47,97,98,99,100,101,102,103. This modern set includes 10,176 individuals (Supplementary Note 2). Loci and individuals with less than 95% call rate as well as a 15-Mb region surrounding the HLA region36 were removed and loci on three previously reported long-range linkage disequilibrium regions on chromosomes 6, 8 and 11 (refs. 104,105) were pruned using PLINK106 (v1.90b3.29). aDNA data were merged to this dataset, correcting for reference allele and strand flips. We kept 445,171 autosomal SNPs after intersecting autosomal SNPs in the 1240K capture with the modern analysis set.


Raw sequence data (bam files) from the 479 newly reported ancient individuals will be available before publication from the European Nucleotide Archive under accession number PRJEB54899. Published genotype data for the present-day British sample are available from the WTCCC via the European Genotype Archive ( ) under accession number EGAD00010000634. Published genotype data for the present-day Irish sample are available from the WTCCC via the European Genotype Archive under accession number EGAD00010000124. Published genotype data for the rest of the present-day European samples are available from the WTCCC via the European Genotype Archive under accession number EGAD00000000120. Published genotype data for the Dutch samples are available by the GoNL request process from The Genome of the Netherlands Data Access Committee (DAC) ( ). The Genome Reference Consortium Human Build 37 (GRCh37) is available via the National Center for Biotechnology Information under accession number PRJNA31257. The revised Cambridge reference sequence is available via the National Center for Biotechnology Information under NCBI Reference Sequence NC_012920.1. Previous published genotype data for ancient individuals were reported by the Reich laboratory in the Allen Ancient DNA Resource v.50.0 ( -ancient-dna-resource-aadr-downloadable-genotypes-present-day-and-ancient-dna-data).


As an open-access journal, European Thyroid Journal articles are immediately available to read on publication, without restriction. The two types of article metrics we measure are (i) more traditional full-text views and pdf downloads, and (ii) Altmetric data, which shows the wider impact of articles in a range of non-traditional sources, such as social media. 041b061a72


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